Publications:

Hagiwara et al. 2015


scientific article | J Nat Prod

Puupehenol, a Potent antioxidant antimicrobial meroterpenoid from a Hawaiian deep-water Dactylospongia sp. sponge

Hagiwara K, Garcia-Hernandez JE, Harper MK, Carroll A, Motti CA, Awaya J, Nguyen HY, Wright AD


Abstract

Abstract From the organic extract of a deep-water Hawaiian sponge Dactylospongia sp., a new potent antioxidant and antimicrobial meroterpenoid, puupehenol (1), was isolated. The structure of 1 was determined using spectroscopic techniques (1H and 13C NMR, MS, IR, UV, [α]D). The known compound puupehenone (2) was also isolated and suggested as a probable artifact of the isolation procedures. Complete unambiguous 1H and 13C NMR data are provided for compounds 1 and 2. Bioassays performed with 1 and 2 showed them both to be very effective antioxidants and to have antimicrobial properties.

Keywords
Meta-data (pending validation)
Depth range
125- 130 m

Mesophotic “mentions”
0 x (total of 3015 words)

Classification
* Focused on 'mesophotic coral ecosystem'

Fields
Biodiversity
Biomedicine
Ecology

Focusgroups
Porifera (Sponges)

Locations
USA - Hawaii

Platforms
Autonomous Underwater Vehicle (AUV)

Author profiles